Innovation
Phosphatidylserine (PS) has emerged as a high-potential, science-backed ingredient in the brain health category—often referred to as the “gold standard for cognitive nutrition.” As the demand for mental performance and healthy aging solutions continues to rise, the global PS market is projected to grow from $120 million in 2025 to $220 million by 2032, with a CAGR of 8.5%. This expanding market presents a strong growth opportunity for brands that choose innovative, high-quality partners like Rimind PS®.
Why Is Phosphatidylserine (PS) So Important for the Brain?
Phosphatidylserine (PS) is a biologically active compound naturally found in the membranes of brain neurons. It’s considered an essential “foundational nutrient” for maintaining normal neural function. Its importance lies in two key roles:
Enhancing neural efficiency: PS regulates membrane protein functions, increases membrane fluidity, and facilitates the efficient transport of nutrients and signaling molecules. This boosts the responsiveness and metabolic activity of brain cells, enhancing cognition, memory, and resistance to aging.
Supporting neurotransmission: As a key structural component of synaptic membranes, PS stabilizes synaptic architecture and modulates the release and reception of neurotransmitters like acetylcholine, dopamine, and serotonin—critical for memory formation and neural signaling.
DHA + PS: PS + DHA: A Powerful Alliance for Brain Health [2]
DHA enhances PS synthesis: DHA is incorporated into neuronal membrane phospholipids, significantly increasing PS production.
PS mediates DHA’s signaling function: PS acts as a signaling platform that enhances the membrane localization and activity of key survival kinases like Akt, Raf-1, and PKC. By boosting PS levels, DHA enables these kinases to function optimally, amplifying its neuroprotective effects.
DHA’s anti-apoptotic effect relies on PS: DHA alone cannot activate survival pathways. Only when it induces PS accumulation can it help kinases relocate, prevent neuronal apoptosis, and protect brain cells.
PS levels depend on DHA: DHA deficiency leads to reduced PS levels in neural tissue, and supplementation with other fatty acids does not restore PS. This underscores PS’s strong dependency on DHA.
Together, DHA and PS support neural membrane signaling and brain protection, working hand in hand to maintain cognitive health and performance.
Backed by Clinical Research: From Teens to Seniors
Memory enhancement in adolescents [3]: In a study of 120 middle school students, taking 100 mg of PS daily for 40 days significantly improved memory performance.
Improved attention in children [4]: A double-blind, randomized study with 36 children aged 4–14 with attention deficits showed that 200 mg/day of PS for two months improved focus.
Cognitive improvement in seniors with MCI [5]: In a study of 79 Japanese elderly individuals with mild cognitive impairment (MCI), 300 mg/day of PS for six months improved cognitive function.
Rimind PS® Boosts Memory and Cognition – Zebrafish T-Maze Study
Richen, in collaboration with the Shandong Academy of Sciences Institute of Biology, conducted a zebrafish “T-maze” behavioral study. The results demonstrated that Rimind PS® effectively improved learning and cognitive performance.
Why Do Leading Brands Choose Rimind PS®?
1. Key contributor to Chinese industry standard
Richen nutritionals is the lead drafter of China’s Phosphatidylserine Industry Standard (QB/T 5821-2023), released in 2023. Choosing Rimind PS® means selecting an ingredient that sets the industry benchmark for quality.
2. Natural and Safe Ingredients
Rimind PS® is derived from non-GMO soy lecithin and produced using advanced enzymatic conversion technology. It’s safe, natural, and suitable for all age groups, from children to seniors.
3. Protected by Patents
Rimind PS® holds three Chinese invention patents and one PCT international patent, offering strong IP protection and ensuring product quality and efficacy. This provides brands with a solid foundation to develop competitive end products.
4. Complete Application Support Across Product Types
Rimind PS® offers a versatile product lineup to support a wide range of applications, making formulation easier and more efficient for brand partners:
Rimind PS® Granules
Free-flowing and non-caking, ideal for tablets and hard capsules. Improves production efficiency and final product stability.
Rimind PS® Powder
Fine and uniform texture, suitable for softgel capsules and gummies. Supports high active ingredient loads while ensuring ease of processing and a pleasant mouthfeel.
Rimind PS® CWD Powder
To Solve the common water solubility issue of PS in the market, Rimind PS® disperses quickly with mild stirring, without noticeable sediment or floating. Perfect for powdered beverages, oral liquids, and dairy-based formulations.
As the lead drafter of the PS industry standard, Rimind PS® is setting the bar for high-quality brain health ingredients. Today, Rimind PS® is widely used in functional foods and dietary supplements, providing trusted ingredients and application support for a growing number of brands.
[1]Dialogues Clin Neurosci.2004;6:351-64
[2] Prostaglandins Leukot Essent Fatty Acids. 2010;82(4-6):165-172.
[3]Chongqing medical journal. 2011,40(30)3. DOICNKISUNCQYX.0.2011-30-005.
[4] Journal of human nutrition and dietetics, 2014, 27 284-291.
[5] Journal of clinical biochemistry and nutrition, 2010, 47(3) 246-255.